I'm puzzling a bit over one of the abbreviations: MEDIAT T, with a line over the A.
In more legible Latin, the two boxes together read:
Ignorantiam meam summa cum invidia mortalium iunctam, ex animo serioque nec sero deplorans, unicum mihi solatium existimo quod id eiusque media?t?t? ministris, tacendo, sperando (rumpantur ut ilia momo) tandem fit surculus arbor fiat.
Which means: "as for my ignorance, which is connected with the utmost resentment of mortals, I deplore it wholeheartedly and seriously, and not only lately, but I consider it my only solace, because/that ... [the bit I don't understand], by being silent, by continuing to hope (that blame may bust its guts!) and last it happens that the sapling becomes a tree."
'rumpantur ut ilia X' seems to pop up in a few other places, where it means effectively 'X can go to hell'. It probably derives from some quotation, but I don't know what.
The picture itself shows one guy standing on a block that says "I swear silence", and another on a block that says "I have hope for the future".